Spectral Changes Induced by Alkaline pH and Specific Chemical Modification of Amino Acid Residues in the Light-Harvesting II Antenna Complex from Ectothiorhodospira sp.

1999 ◽  
Vol 69 (3) ◽  
pp. 275 ◽  
Author(s):  
André Buche ◽  
Rafael Picorel
Keyword(s):  
Amino Acid ◽  
Chemical Modification ◽  
Light Harvesting ◽  
Amino Acid Residues ◽  
Alkaline Ph ◽  
Specific Chemical ◽  
Antenna Complex ◽  
Spectral Changes ◽  
Specific Chemical Modification

scholarly journals Identification of amino acid residues essential for enzyme activity of sheep liver 5,10-methylenetetrahydrofolate reductase

1986 ◽  
Vol 236 (1) ◽  
pp. 295-298 ◽  
Author(s):  
K Varalakshmi ◽  
H S Savithri ◽  
N A Rao
Keyword(s):  
Enzyme Activity ◽  
Amino Acid ◽  
Chemical Modification ◽  
Rate Constants ◽  
Methylenetetrahydrofolate Reductase ◽  
Second Order ◽  
Amino Acid Residues ◽  
Specific Chemical ◽  
Sheep Liver ◽  
Specific Chemical Modification

Sheep liver 5,10-methylenetetrahydrofolate reductase was subjected to specific chemical modification with phenylglyoxal, diethyl pyrocarbonate and N-bromosuccinimide. The second-order rate constants for inactivation were calculated to be 54 M-1 X min-1, 103 M-1 X min-1 and 154 M-1 X min-1 respectively. This inactivation could be prevented by incubation with substrates or products, suggesting that the residues modified, namely arginine, histidine and tryptophan, are essential for enzyme activity.

IL-4 Analogues with Site-Specific Chemical Modification at Position 121 Inhibit IL-4 and IL-13 Biological Activities

2013 ◽  
Vol 25 (1) ◽  
pp. 52-62 ◽  
Author(s):  
Viswanadham Duppatla ◽  
Maja Gjorgjevikj ◽  
Werner Schmitz ◽  
Heike M. Hermanns ◽  
Carmen M. Schäfer ◽  
...  
Keyword(s):  
Chemical Modification ◽  
Biological Activities ◽  
Specific Chemical ◽  
Site Specific ◽  
Specific Chemical Modification

scholarly journals Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification

2006 ◽  
Vol 34 (17) ◽  
pp. 4900-4911 ◽  
Author(s):  
Sujiet Puthenveetil ◽  
Landon Whitby ◽  
Jin Ren ◽  
Kevin Kelnar ◽  
Joseph F. Krebs ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Chemical Modification ◽  
Dependent Protein Kinase ◽  
Specific Chemical ◽  
Site Specific ◽  
Specific Chemical Modification ◽  
Dependent Protein
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